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Olfactory cells for spinal cord repair
Griffith University researchers are focused on improving the effectiveness of the olfactory cells in repairing the spinal cord. This will lead to a Phase I/IIa clinical trial of patients, whereby a glial bridge made of olfactory cells will be transplanted into patients with contusion spinal cord injury followed by intensive physiotherapy for 12 months.
Unique selling point/competitive advantage
Griffith University researchers combine improved cell purification and culturing techniques with natural product discovery to identify compounds that stimulate the cells.
New engineering approaches have vastly improved:
- 3D growth of cells to generate cell bridges for transplantation
- the use of robotic high throughput screening of 3D cell culture assays.
Investment or collaboration opportunities
Griffith University is seeking investors and collaborators to help support the clinical trial cell purification through:
- 3D cell culturing
- natural product discovery
- high throughput drug screening
- animal spinal surgery
- human spinal surgery
- GMP production of cells
- transport of human cell products
- compliance/reporting/clinical trial management.
Dr James St John
Head of the Clem Jones Centre for Neurobiology and Stem Cell Research
Phone: +61 7 3735 3660
Learn more about Dr James St John.
- Last reviewed: 17 Jul 2019
- Last updated: 30 May 2018